Molecular & Cellular Biology

Revealing the secrets of nature & educating next generation of science innovators

Differentiation, Development, and Evolution

Differentiation, Development, and Evolution

Differentiation, Development, and Evolution

Creating complex plant or animal tissues demands that cells adopt different fates by differentiating from stem cells into distinct cell types. Proper differentiation is essential for normal development, and defects in differentiation are a hallmark of cancer. Moreover, over evolutionary time much of the amazing diversity of life has arisen through changes in cellular differentiation and development.

Associated Faculty

Our research group integrates computational systems biology and population genetics to understand the function and evolution of the complex molecular networks that underlie life. We build and analyze mathematical simulations of protein networks to probe deeper into their function than experiments can. We... Read More
The Kacar Lab investigates key questions regarding molecular mechanisms of evolution, the origins of life and the distribution of life throughout our universe. We are interested in understanding life’s working strategies at the molecular level and how the ancestral behaviors of proteins and... Read More
I am interested in exploring the genetic basis of morphological diversity. To do this, I ask how developmental regulatory networks known to pattern a particular aspect of morphology in one organism are modified in other related organisms. At the moment, the focus of the lab is on the evolution of arthropod... Read More
Joyce Schroeder, PhD, holds research interests in the area of breast cancer progression and invasion. Transgenic mouse models of spontaneous carcinoma are used to understand the molecular mechanisms of primary tumor development and metastatic progression. Tumor growth and invasion is a complex process... Read More
1. Translational control in glia-neural stem cell interactions We have recently discovered a novel role for the RNA binding protein, FMRP, in neural stem cells exit from quiescence, a universal mechanism utilized by stem and progenitor cells across phyla. Furthermore, using tissue specific RNAi we found... Read More