spe-11

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Genetic Position I -0.10

Physical Location F48C1

Sequence Genomic DNA: Genbank Accession U36483

Cloned By Strome Lab

Homologies

Mutant Alleles
hc77ts, hc90

Strains available from CGC

Effect of Mutations Paternal effect: Hermaphrodites and males produce motile sperm that fertilize oocytes leading to abnormal early development. Transcript present only in sperm, but forced transgene expression in oocyte can rescue Spe phenotype; SPE-11 in perinuclear halo of mature sperm.

References
Hill DP, et al. A sperm-supplied product essential for initiation of normal embryogenesis in Caenorhabditis elegans is encoded by the paternal-effect embryonic-lethal gene, spe-11. Dev Biol. 1989 Nov 1; 136(1): 154-166.

Browning H. and S Strome A sperm-supplied factor required for embryogenesis in C. elegans. Development. 1996 Jan 1; 122(1): 391-404.

ACEDB/WormPD ACEDB data
WormPD data

http://www.mcb.arizona.edu/wardlab/spegenes/spe11.html
All Contents Copyright © 2000. All rights reserved.
Last Modified: July 12, 2000
Paul Muhlrad pmuhlrad@u.arizona.edu

Genetic Position	I -0.10
Physical Location	F48C1
Sequence	Genomic DNA: Genbank Accession U36483
Cloned By	Strome Lab
Homologies
Mutant Alleles	hc77ts, hc90 Strains available from CGC
Effect of Mutations	Paternal effect: Hermaphrodites and males produce motile sperm that fertilize oocytes leading to abnormal early development. Transcript present only in sperm, but forced transgene expression in oocyte can rescue Spe phenotype; SPE-11 in perinuclear halo of mature sperm.
References	Hill DP, et al. A sperm-supplied product essential for initiation of normal embryogenesis in Caenorhabditis elegans is encoded by the paternal-effect embryonic-lethal gene, spe-11. Dev Biol. 1989 Nov 1; 136(1): 154-166. Browning H. and S Strome A sperm-supplied factor required for embryogenesis in C. elegans. Development. 1996 Jan 1; 122(1): 391-404.
ACEDB/WormPD	ACEDB data WormPD data