spe-26 |
| Genetic Position | IV 4.58 (see genetic map in acedb) |
| Physical Location | C26H10 (see cosmid info in acedb) |
| Sequence | Genomic DNA: Genbank Accession U20142 Protein: Genbank Accession 644842 Graphical map and sequence in acedb |
| Cloned By | Ward Lab |
| Homologies | Kelch/Scruin repeats. Possible actin-binding domain. |
| Mutant Alleles | it112ts, hc138ts, hc139ts, hc140ts, eb8 |
| Effect of Mutations | Early spermatocyte arrest: mis-segregated chromosomes, mislocalized actin. No spermatids made. Lengthened lifespan. |
| References | Varkey, et al. The Caenorhabditis elegans spe-26 gene is necessary to form spermatids and encodes a protein similar to the actin-associated proteins kelch and scruin. Genes Dev. 1995 May 1; 9(9): 1074-1086. Van Voorhies, Production of sperm reduces nematode lifespan. Nature. 1992 Dec 3; 360(6403): 456-458.
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| ACEDB/WormPD | ACEDB
data WormPD data |