spe-27

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Genetic Position IV 2.51 (see genetic map in acedb)

Physical Location DC12 (see cosmid info in acedb)

Sequence
Genomic DNA: Genbank Accession U37713

Protein: Genbank Accession 1022815

Cloned By Ward Lab

Homologies none

Mutant Alleles
it110, it132ts, hc161

Strains available from CGC

Effect of Mutations Defective in receiving or processing the hermaphrodite spermiogenesis initiation signal: unmated hermaphrodites are self-sterile because their spermatids fail to undergo spermiogenesis; mated hermaphrodites are self- and outcross-fertile. Males are fertile. Spermatids from both males and hermaphrodites form spikes rather than pseudopods when exposed to pronase. Suppressible by spe-6 suppressor alleles.

References
Minniti AN, et al. Genetic and molecular analysis of spe-27, a gene required for spermiogenesis in Caenorhabditis elegans hermaphrodites. Genetics. 1996 May 1; 143(1): 213-223.

LaMunyon CW, et al. Assessing the viability of mutant and manipulated sperm by artificial insemination of Caenorhabditis elegans. Genetics. 1994 Nov 1; 138(3): 689-692.

ACEDB/WormPD
ACEDB data
WormPD data

Genetic Position	IV 2.51 (see genetic map in acedb)
Physical Location	DC12 (see cosmid info in acedb)
Sequence	Genomic DNA: Genbank Accession U37713 Protein: Genbank Accession 1022815
Cloned By	Ward Lab
Homologies	none
Mutant Alleles	it110, it132ts, hc161 Strains available from CGC
Effect of Mutations	Defective in receiving or processing the hermaphrodite spermiogenesis initiation signal: unmated hermaphrodites are self-sterile because their spermatids fail to undergo spermiogenesis; mated hermaphrodites are self- and outcross-fertile. Males are fertile. Spermatids from both males and hermaphrodites form spikes rather than pseudopods when exposed to pronase. Suppressible by spe-6 suppressor alleles.
References	Minniti AN, et al. Genetic and molecular analysis of spe-27, a gene required for spermiogenesis in Caenorhabditis elegans hermaphrodites. Genetics. 1996 May 1; 143(1): 213-223. LaMunyon CW, et al. Assessing the viability of mutant and manipulated sperm by artificial insemination of Caenorhabditis elegans. Genetics. 1994 Nov 1; 138(3): 689-692.
ACEDB/WormPD	ACEDB data WormPD data