spe-8

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Genetic Position I -17.38

Physical Location

Sequence

Cloned By Not cloned

Homologies

Mutant Alleles
hc40, hc50, hc53, hc79, hc85, hc108, hc134ts

Strains available from CGC

Effect of Mutations Defective in receiving or processing the hermaphrodite spermiogenesis initiation signal: unmated hermaphrodites are self-sterile because their spermatids fail to undergo spermiogenesis; mated hermaphrodites are self- and outcross-fertile. Males are fertile. Spermatids from both males and hermaphrodites form spikes rather than pseudopods when exposed to pronase. Suppressible by spe-6 suppressor alleles.

References
L'Hernault SW, et al. Developmental genetics of chromosome I spermatogenesis-defective mutants in the nematode Caenorhabditis elegans. Genetics. 1988 Oct 1; 120(2): 435-452.

Shakes DC, and S Ward Initiation of spermiogenesis in C. elegans: a pharmacological and genetic analysis. Dev Biol. 1989 Jul 1; 134(1): 189-200.

LaMunyon CW, et al. Assessing the viability of mutant and manipulated sperm by artificial insemination of Caenorhabditis elegans. Genetics. 1994 Nov 1; 138(3): 689-692.

Genetic Position	I -17.38
Physical Location
Sequence
Cloned By	Not cloned
Homologies
Mutant Alleles	hc40, hc50, hc53, hc79, hc85, hc108, hc134ts Strains available from CGC
Effect of Mutations	Defective in receiving or processing the hermaphrodite spermiogenesis initiation signal: unmated hermaphrodites are self-sterile because their spermatids fail to undergo spermiogenesis; mated hermaphrodites are self- and outcross-fertile. Males are fertile. Spermatids from both males and hermaphrodites form spikes rather than pseudopods when exposed to pronase. Suppressible by spe-6 suppressor alleles.
References	L'Hernault SW, et al. Developmental genetics of chromosome I spermatogenesis-defective mutants in the nematode Caenorhabditis elegans. Genetics. 1988 Oct 1; 120(2): 435-452. Shakes DC, and S Ward Initiation of spermiogenesis in C. elegans: a pharmacological and genetic analysis. Dev Biol. 1989 Jul 1; 134(1): 189-200. LaMunyon CW, et al. Assessing the viability of mutant and manipulated sperm by artificial insemination of Caenorhabditis elegans. Genetics. 1994 Nov 1; 138(3): 689-692.